Cranial Cooling Concussion Hub

Understanding concussion.

An educational hub: what a concussion actually is, how it’s assessed, and the tools and measurements clinicians use — written plainly, sized to the evidence, and device-agnostic. This explains the landscape the Concussion Cooling Study is built on; it is not medical advice.

What's inside the hub

Concussion, in plain parts.

A plain-language tour of the landscape the Concussion Cooling Study is built on — what the injury is, how it's assessed, the tools clinicians use, and the biological signals that make it measurable.

The basics

A functional injury, not usually a structural one.

A concussion (mild traumatic brain injury) is a transient disruption of how the brain functions, driven by a metabolic disturbance rather than visible structural damage.WP-03 That is why conventional imaging — designed to find bleeds and fractures — is, by design, insensitive to it: most sport concussions are CT-negative.WP-04

One manifestation of that metabolic disturbance is a brief rise in brain temperature, and because neuronal energy demand rises with temperature, the acute window is the period clinicians watch most closely.WP-03

In plain terms

  • It is a disturbance of brain function, not usually of structure.
  • A normal scan does not rule it out.
  • Symptoms can evolve over hours to days.
  • Recovery is individual; assessment is repeated over time.

How it’s assessed

Recognise, remove, assess, return — gradually.

Current consensus care emphasises recognising the injury, removing the athlete from play, assessing with validated tools, and a graduated, clinician-governed return to activity.1 Assessment draws on several complementary layers.

Symptom inventories

Structured self-report of headache, fog, balance, light and noise sensitivity, and mood — tracked over time against the person’s own baseline.

Neurocognitive & balance testing

Validated, often FDA-cleared platforms measure reaction time, memory, and postural stability — ideally compared to a pre-season baseline.

Clinical judgment

The clinician integrates the above with the mechanism of injury and exam findings. Return-to-play is a clinical decision, never an automatic score.

The assessment tools

What ImPACT and Sway are.

Neurocognitive

ImPACT

A computerised neurocognitive test (Immediate Post-Concussion Assessment and Cognitive Testing) widely used to establish a baseline before a season and to measure cognition — memory, processing speed, reaction time — after a suspected concussion. It is one validated input to a clinician’s decision, not a stand-alone diagnosis.

Official ImPACT resource
Balance & cognition

Sway

A mobile platform that uses a device’s motion sensors to measure balance and postural stability alongside cognitive tasks, enabling baseline and sideline assessment. Like ImPACT, it contributes objective data to a clinician-governed evaluation.

Official Sway resource

Named platforms are described for education and are illustrative of validated tools; mention here is not a statement of partnership. Several cleared platforms exist (ImPACT, Sway, King-Devick); selection rests with the clinical team.

The biological axis

Blood-based biomarkers, briefly.

Fluid biomarkers add an objective, quantitative signal alongside symptoms and cognition. They are used here as intermediate endpoints, not as a diagnosis of concussion.

  • GFAP & UCH-L1 — acute markers that rise within hours; the basis of FDA-cleared blood testing whose cleared use is helping exclude CT-detectable injury, not grading concussion.WP-04
  • NfL — a delayed, persistent marker of axonal injury, better suited to tracking cumulative and longer-term burden.WP-04
Read the biomarker clinical exhibit

Evidentiary status

Established: GFAP/UCH-L1 for acute CT-triage; NfL as a sensitive axonal-injury marker.

Not established: using these to grade concussion severity or to monitor recovery — these remain study questions, treated as exploratory.

Where the hub meets the study

The Concussion Cooling Study.

The hub explains the landscape; the study tests one question within it — whether cooling the brain early changes the course of injury. Cooling is layered onto standard care; clinical judgment governs return-to-play; the study is device-agnostic and admits any cooling method investigators approve.

Short-term arm

Symptom trajectory and recovery time, acute biomarkers (GFAP / UCH-L1), instrumented thermal data, and comfort/adherence — within a season.

Long-term arm

Cumulative head-impact exposure, the axonal marker NfL, and serial cognition across and beyond a career — contributing to the long-horizon question rather than presuming to resolve it.

Honest about the evidence. Early head-cooling findings in sport concussion are from small samples and should be read as encouraging, not conclusive. Whether acute cooling alters long-term outcomes remains to be shown.456
Governance. Device-agnostic and clinician-governed; minors require guardian consent; names appear only in an athletics context with consent, never on the clinical side. Nothing here is a treatment claim or medical advice.
Take part in the study →Collaborate on the study →
References
  1. Patricios JS, et al. Consensus statement on concussion in sport — 6th International Conference, Amsterdam 2022. Br J Sports Med. 2023;57(11):695–711.
  2. Cabanac M, Caputa M. Natural selective cooling of the human brain. J Physiol. 1979;286:255–264.
  3. Wang H, et al. Rapid and selective cerebral hypothermia achieved using a cooling helmet. J Neurosurg. 2004;100(2):272–277.
  4. Gard A, et al. Selective head–neck cooling after concussion shortens return-to-play in ice hockey players. Concussion. 2021;6(2):CNC90.
  5. Congeni J, et al. Preliminary safety and efficacy of head-and-neck cooling after concussion in adolescent athletes: a randomized pilot trial. Clin J Sport Med. 2022;32(4):341–347.
  6. Walter AE, et al. Selective head cooling in the acute phase of concussive injury: a neuroimaging study. Front Neurol. 2023;14:1272374.

The thermal-dimension and biomarker detail behind the claims marked WP-03 and WP-04 is held in those papers. ImPACT and Sway link to their official resources above. Descriptive, not diagnostic; not medical advice.